Complementation Test ofRpe65Knockout and Tvrm148

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15 صفحه اول

Complementation.

Mutations in many genes can result in a similar phenotype. Finding a number of mutants with the same phenotype tells you little about how many genes you are dealing with, and how mutable those genes are until you can assign those mutations to genetic loci. The genetic assay for gene assignment is called the complementation test. The simplicity and robustness of this test makes it a fundamental ...

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ژورنال

عنوان ژورنال: Investigative Opthalmology & Visual Science

سال: 2013

ISSN: 1552-5783

DOI: 10.1167/iovs.13-12336